Bulk Tesamorelin
GHRH analog and growth-hormone axis research research material, supplied as a lyophilized reference standard. >=99% by HPLC.
Available Sizes & Pricing
| Size | Price per vial (USD) |
|---|---|
| 10 mg | $99.95 |
A minimum inquiry quantity of 10 vials applies across requested products. Inquire for bulk purchase or larger lot quantities →
Bulk Tesamorelin Specifications
| CAS Number | 901758-09-6 |
|---|---|
| Molecular Formula | C221H366N72O67S |
| Molecular Weight | 5135.8 g/mol |
| Purity | >=99% by HPLC |
| Storage | Store lyophilized material at -20 C. Avoid repeated freeze-thaw cycles after reconstitution. |
What Is Tesamorelin?
Tesamorelin is cataloged for controlled laboratory workflows focused on ghrh analog and growth-hormone axis research. Its lot-specific analytical documentation should be reviewed alongside the receiving laboratory's established handling and assay-validation procedures. For laboratory research use only - not for human or veterinary use.
Tesamorelin Research Context
Tesamorelin is a synthetic GHRH analog in which trans-3-hexenoic acid is conjugated to the N-terminus of GHRH(1-44) to improve stability against enzymatic cleavage. In research settings it serves as a stable-form GHRH tool compound for GHRHR binding assays and comparative stability studies against native GHRH fragments such as sermorelin. Its additional carbon chain is a useful variable when examining how N-terminal modifications influence receptor binding kinetics.
The trans-hex-2-enoic acid adduct shields the N-terminal tyrosine from DPP-IV-mediated cleavage while preserving GHRHR binding and Gs-cAMP signaling capacity. Researchers use this stability advantage in cell assays where native GHRH would be rapidly inactivated by media proteases.
Study-Design Considerations
- The N-terminal fatty-acid modification can reduce aqueous solubility; prepare dilutions in phosphate-buffered saline containing 0.1% BSA to prevent adsorption to plastic labware at nanomolar concentrations.
- Side-by-side stability testing with sermorelin in conditioned media is a productive experimental design to quantify the protection conferred by the trans-hexenoic acid modification.
Interpretation Limits
Stability advantages observed in cell-culture media systems do not necessarily predict in vivo half-life, and binding constants measured in recombinant systems may differ from primary tissue preparations.
Tesamorelin Research Applications
- GHRH receptor assays
- Pituitary signaling research
- Comparative peptide studies
Source Records
Use the following scientific and compound-record sources when developing a laboratory-specific protocol; they do not replace method validation for a particular lot or assay.
Related Research Materials
- Bulk Sermorelin — GHRH fragment and pituitary signaling research research material, supplied as a lyophilized reference standard. >=99% by HPLC.
- Bulk Ipamorelin — ghrelin receptor and growth-hormone secretagogue research research material, supplied as a lyophilized reference standard. >=99% by HPLC.
Buy Bulk Tesamorelin for Research
Bulk Peptides supplies bulk Tesamorelin to institutional laboratories, CROs, and research facilities across the United States. Every lot is characterized by reverse-phase HPLC at 220 nm and confirmed by electrospray ionization mass spectrometry before shipping. A lot-specific Certificate of Analysis documents both results for your records.
Bulk Tesamorelin is available in the catalog sizes above. A minimum inquiry quantity of 10 vials applies; contact us for larger requirements or custom synthesis quotes. All products are for laboratory research use only (RUO) — not for human or veterinary use.
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