Bulk Ipamorelin
ghrelin receptor and growth-hormone secretagogue research research material, supplied as a lyophilized reference standard. >=99% by HPLC.
Available Sizes & Pricing
| Size | Price per vial (USD) |
|---|---|
| 5 mg | $79.95 |
| 10 mg | $109.95 |
A minimum inquiry quantity of 10 vials applies across requested products. Inquire for bulk purchase or larger lot quantities →
Bulk Ipamorelin Specifications
| CAS Number | 170851-70-4 |
|---|---|
| Molecular Formula | C38H49N9O5 |
| Molecular Weight | 711.9 g/mol |
| Purity | >=99% by HPLC |
| Storage | Store lyophilized material at -20 C. Avoid repeated freeze-thaw cycles after reconstitution. |
What Is Ipamorelin?
Ipamorelin is cataloged for controlled laboratory workflows focused on ghrelin receptor and growth-hormone secretagogue research. Its lot-specific analytical documentation should be reviewed alongside the receiving laboratory's established handling and assay-validation procedures. For laboratory research use only - not for human or veterinary use.
Ipamorelin Research Context
Ipamorelin is a synthetic pentapeptide growth-hormone secretagogue that selectively activates the growth-hormone secretagogue receptor (GHSR-1a) with minimal off-target activity at receptors for cortisol, prolactin, and ACTH in cell-based systems. Its high receptor selectivity makes it a preferred reference tool compound for isolating GHSR-1a-specific downstream signaling from broader ghrelin-pathway effects. The defined molecular weight and sequence (Aib-His-D-2Nal-D-Phe-Lys-NH₂) support its use as an analytical comparator.
Ipamorelin mimics acyl-ghrelin at GHSR-1a, coupling to Gq/11 proteins and mobilizing intracellular calcium in receptor-expressing cells. Unlike natural ghrelin, it lacks the octanoyl modification, which allows researchers to attribute GHSR-dependent effects without confounding acylation chemistry.
Study-Design Considerations
- Verify peptide identity by mass spectrometry before receptor binding work because the amidated C-terminus is required for full GHSR-1a activity and is sensitive to carboxypeptidase contamination in cell culture.
- Use GHSR-1a-null cells or the selective antagonist [D-Lys³]-GHRP-6 as negative controls when measuring calcium flux to confirm receptor specificity.
Interpretation Limits
Ipamorelin's high GHSR-1a selectivity observed in recombinant cell lines may not fully represent receptor expression patterns in primary or native tissue preparations.
Ipamorelin Research Applications
- GHSR binding studies
- Pituitary cell assays
- Secretagogue selectivity profiling
Source Records
Use the following scientific and compound-record sources when developing a laboratory-specific protocol; they do not replace method validation for a particular lot or assay.
Related Research Materials
- Bulk Sermorelin — GHRH fragment and pituitary signaling research research material, supplied as a lyophilized reference standard. >=99% by HPLC.
- Bulk Tesamorelin — GHRH analog and growth-hormone axis research research material, supplied as a lyophilized reference standard. >=99% by HPLC.
Buy Bulk Ipamorelin for Research
Bulk Peptides supplies bulk Ipamorelin to institutional laboratories, CROs, and research facilities across the United States. Every lot is characterized by reverse-phase HPLC at 220 nm and confirmed by electrospray ionization mass spectrometry before shipping. A lot-specific Certificate of Analysis documents both results for your records.
Bulk Ipamorelin is available in the catalog sizes above. A minimum inquiry quantity of 10 vials applies; contact us for larger requirements or custom synthesis quotes. All products are for laboratory research use only (RUO) — not for human or veterinary use.
See HPLC & COA quality standards · Shipping & payment information · Full bulk peptides catalog