Bulk SS-31 (Elamipretide)
mitochondrial membrane and oxidative-stress research research material, supplied as a lyophilized reference standard. >=99% by HPLC.
Available Sizes & Pricing
| Size | Price per vial (USD) |
|---|---|
| 1 vial | $59.95 |
A minimum inquiry quantity of 10 vials applies across requested products. Inquire for bulk purchase or larger lot quantities →
Bulk SS-31 (Elamipretide) Specifications
| CAS Number | See lot-specific COA |
|---|---|
| Molecular Formula | See lot-specific COA |
| Molecular Weight | See lot-specific COA |
| Purity | >=99% by HPLC |
| Storage | Store lyophilized material at -20 C. Avoid repeated freeze-thaw cycles after reconstitution. |
What Is SS-31 (Elamipretide)?
SS-31 (Elamipretide) is cataloged for controlled laboratory workflows focused on mitochondrial membrane and oxidative-stress research. Its lot-specific analytical documentation should be reviewed alongside the receiving laboratory's established handling and assay-validation procedures. For laboratory research use only - not for human or veterinary use.
SS-31 (Elamipretide) Research Context
SS-31 (elamipretide; D-Arg-2′6′-Dmt-Lys-Phe-NH₂) is a synthetic aromatic-cationic tetrapeptide designed to target the inner mitochondrial membrane through electrostatic and aromatic interactions with cardiolipin. In isolated mitochondria and cell-based models it has been used to study the relationship between cardiolipin oxidation, electron-transport chain efficiency, and mitochondrial membrane potential. Its mitochondria-targeting properties make it a useful tool for oxidative-stress pathway research.
SS-31 concentrates at the inner mitochondrial membrane by interacting with the anionic phospholipid cardiolipin through alternating cationic and aromatic residues. In cell models experiencing oxidative stress, SS-31 treatment is associated with reduced cytochrome c release and preserved complex I/IV activities, suggesting a role in stabilizing electron-transport supercomplexes.
Study-Design Considerations
- SS-31 contains D-amino acids and a non-standard residue (2′,6′-dimethyltyrosine); confirm peptide identity by HPLC and MS before use, as racemization artifacts from synthesis can reduce mitochondrial targeting efficiency.
- JC-1 or TMRE-based mitochondrial membrane potential assays should be combined with viability markers to distinguish genuine membrane-potential changes from cytotoxic depolarization.
Interpretation Limits
Cardiolipin interaction data obtained in isolated mitochondria systems may differ from intact-cell contexts where competing inner-membrane proteins and lipid dynamics are present.
SS-31 (Elamipretide) Research Applications
- Mitochondrial models
- Oxidative-stress assays
- Membrane interaction studies
Source Records
Use the following scientific and compound-record sources when developing a laboratory-specific protocol; they do not replace method validation for a particular lot or assay.
Related Research Materials
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Buy Bulk SS-31 (Elamipretide) for Research
Bulk Peptides supplies bulk SS-31 (Elamipretide) to institutional laboratories, CROs, and research facilities across the United States. Every lot is characterized by reverse-phase HPLC at 220 nm and confirmed by electrospray ionization mass spectrometry before shipping. A lot-specific Certificate of Analysis documents both results for your records.
Bulk SS-31 (Elamipretide) is available in the catalog sizes above. A minimum inquiry quantity of 10 vials applies; contact us for larger requirements or custom synthesis quotes. All products are for laboratory research use only (RUO) — not for human or veterinary use.
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