Bulk Epitalon
telomere and cellular aging models research material, supplied as a lyophilized reference standard. >=99% by HPLC.
Available Sizes & Pricing
| Size | Price per vial (USD) |
|---|---|
| 10 mg | $69.95 |
A minimum inquiry quantity of 10 vials applies across requested products. Inquire for bulk purchase or larger lot quantities →
Bulk Epitalon Specifications
| CAS Number | See lot-specific COA |
|---|---|
| Molecular Formula | See lot-specific COA |
| Molecular Weight | See lot-specific COA |
| Purity | >=99% by HPLC |
| Storage | Store lyophilized material at -20 C. Avoid repeated freeze-thaw cycles after reconstitution. |
What Is Epitalon?
Epitalon is cataloged for controlled laboratory workflows focused on telomere and cellular aging models. Its lot-specific analytical documentation should be reviewed alongside the receiving laboratory's established handling and assay-validation procedures. For laboratory research use only - not for human or veterinary use.
Epitalon Research Context
Epitalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the natural pineal gland extract epithalamin. It has been studied in cellular aging models primarily as a putative telomerase pathway modulator; some cell-line studies report changes in telomere length and cell cycle progression in the presence of exogenous epitalon, though mechanistic targets remain incompletely characterized. It also appears in research examining circadian gene expression in pineal and hypothalamic cell models.
Epitalon's proposed mechanism involves upregulation of telomerase reverse transcriptase (TERT) expression in senescent cell lines, though direct binding to telomerase components has not been confirmed crystallographically. Secondary research interest focuses on its influence on melatonin-pathway genes in circadian models.
Study-Design Considerations
- Because epitalon effects on telomere length require multiple cell divisions to manifest, endpoint readouts should include sufficient passage counts to detect statistically meaningful changes in telomere signal.
- Include scrambled-sequence tetrapeptide and vehicle controls in gene-expression assays to confirm that observed transcriptional effects are sequence-specific rather than generic peptide responses.
Interpretation Limits
Telomere-related findings from cell-line studies are confounded by artificial immortalization; results should be interpreted cautiously relative to primary cell systems.
Epitalon Research Applications
- Cellular aging models
- Telomere-related research
- Circadian pathway studies
Source Records
Use the following scientific and compound-record sources when developing a laboratory-specific protocol; they do not replace method validation for a particular lot or assay.
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Buy Bulk Epitalon for Research
Bulk Peptides supplies bulk Epitalon to institutional laboratories, CROs, and research facilities across the United States. Every lot is characterized by reverse-phase HPLC at 220 nm and confirmed by electrospray ionization mass spectrometry before shipping. A lot-specific Certificate of Analysis documents both results for your records.
Bulk Epitalon is available in the catalog sizes above. A minimum inquiry quantity of 10 vials applies; contact us for larger requirements or custom synthesis quotes. All products are for laboratory research use only (RUO) — not for human or veterinary use.
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