Bulk Semax
neuropeptide signaling research research material, supplied as a lyophilized reference standard. >=99% by HPLC.
Available Sizes & Pricing
| Size | Price per vial (USD) |
|---|---|
| 10 mg | $49.95 |
A minimum inquiry quantity of 10 vials applies across requested products. Inquire for bulk purchase or larger lot quantities →
Bulk Semax Specifications
| CAS Number | See lot-specific COA |
|---|---|
| Molecular Formula | See lot-specific COA |
| Molecular Weight | See lot-specific COA |
| Purity | >=99% by HPLC |
| Storage | Store lyophilized material at -20 C. Avoid repeated freeze-thaw cycles after reconstitution. |
What Is Semax?
Semax is cataloged for controlled laboratory workflows focused on neuropeptide signaling research. Its lot-specific analytical documentation should be reviewed alongside the receiving laboratory's established handling and assay-validation procedures. For laboratory research use only - not for human or veterinary use.
Semax Research Context
Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) derived from the ACTH(4-10) sequence with a C-terminal Pro-Gly-Pro extension that slows enzymatic degradation. It has been studied in neuroscience research as a BDNF-signaling modulator in neuronal cell models, where it is reported to influence TrkB pathway activity and downstream CREB phosphorylation in cortical and hippocampal cell lines. Its proline-rich C-terminus provides resistance to carboxypeptidases relevant in CNS cell culture media.
Semax is proposed to interact with BDNF-pathway components upstream of TrkB phosphorylation, though a direct receptor has not been definitively identified. Secondary research interest focuses on its influence on melanocortin receptor subtypes inherited from its ACTH fragment parent sequence.
Study-Design Considerations
- Because Semax's proposed BDNF-pathway activity occurs at nanomolar concentrations in some cell assays, use ultrasensitive ELISA or phospho-Western methods (anti-pTrkB, anti-pCREB) to detect low-magnitude signaling changes reliably.
- Include recombinant BDNF as a positive control in every TrkB-pathway experiment to confirm that the assay system is sensitive enough to detect the reference pathway independently of Semax treatment.
Interpretation Limits
The molecular target of Semax in neural signaling remains incompletely characterized, which constrains mechanistic interpretation of cell-based results.
Semax Research Applications
- Neural cell signaling
- Neuropeptide receptor studies
- Stress-pathway research
Source Records
Use the following scientific and compound-record sources when developing a laboratory-specific protocol; they do not replace method validation for a particular lot or assay.
Related Research Materials
- Bulk Selank — neuropeptide and stress-pathway research research material, supplied as a lyophilized reference standard. >=99% by HPLC.
- Bulk Kisspeptin-10 — kisspeptin receptor and neuroendocrine signaling research research material, supplied as a lyophilized reference standard. >=99% by HPLC.
Buy Bulk Semax for Research
Bulk Peptides supplies bulk Semax to institutional laboratories, CROs, and research facilities across the United States. Every lot is characterized by reverse-phase HPLC at 220 nm and confirmed by electrospray ionization mass spectrometry before shipping. A lot-specific Certificate of Analysis documents both results for your records.
Bulk Semax is available in the catalog sizes above. A minimum inquiry quantity of 10 vials applies; contact us for larger requirements or custom synthesis quotes. All products are for laboratory research use only (RUO) — not for human or veterinary use.
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