Bulk KPV
tripeptide and cellular signaling research research material, supplied as a lyophilized reference standard. >=99% by HPLC.
Available Sizes & Pricing
| Size | Price per vial (USD) |
|---|---|
| 5 mg | $44.95 |
| 10 mg | $59.95 |
A minimum inquiry quantity of 10 vials applies across requested products. Inquire for bulk purchase or larger lot quantities →
Bulk KPV Specifications
| CAS Number | See lot-specific COA |
|---|---|
| Molecular Formula | See lot-specific COA |
| Molecular Weight | See lot-specific COA |
| Purity | >=99% by HPLC |
| Storage | Store lyophilized material at -20 C. Avoid repeated freeze-thaw cycles after reconstitution. |
What Is KPV?
KPV is cataloged for controlled laboratory workflows focused on tripeptide and cellular signaling research. Its lot-specific analytical documentation should be reviewed alongside the receiving laboratory's established handling and assay-validation procedures. For laboratory research use only - not for human or veterinary use.
KPV Research Context
KPV is a C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone (α-MSH 11-13; Lys-Pro-Val). It is the minimal active sequence proposed to retain some melanocortin-receptor interaction capacity from the parent α-MSH molecule. In in vitro models it has been examined for effects on NF-κB pathway activation and pro-inflammatory cytokine expression in epithelial cell lines, independent of full-length α-MSH receptor occupancy.
KPV has been studied for potential interactions with MC1R and intracellular pathways that modulate NF-κB nuclear translocation in stimulated epithelial cells. Its small size (MW ~340 Da) and high aqueous solubility simplify delivery in cell-culture systems compared with the full 13-residue α-MSH.
Study-Design Considerations
- Due to its very small size, KPV can pass through many dialysis membranes; use ultrafiltration with a 1 kDa MWCO membrane when removing free peptide from binding-assay samples.
- Include full-length α-MSH as a positive comparator in any signaling assay to confirm whether KPV responses are attributable to the C-terminal tripeptide epitope or require the full sequence.
Interpretation Limits
The biological relevance of KPV's in vitro effects depends heavily on the cell model and stimulation context used; results from one cell type may not generalize to others.
KPV Research Applications
- Cellular signaling assays
- Peptide-fragment studies
- In vitro response profiling
Source Records
Use the following scientific and compound-record sources when developing a laboratory-specific protocol; they do not replace method validation for a particular lot or assay.
Related Research Materials
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- Bulk GHK-Cu — copper-peptide and extracellular-matrix signaling research material, supplied as a lyophilized reference standard. >=99% by HPLC.
Buy Bulk KPV for Research
Bulk Peptides supplies bulk KPV to institutional laboratories, CROs, and research facilities across the United States. Every lot is characterized by reverse-phase HPLC at 220 nm and confirmed by electrospray ionization mass spectrometry before shipping. A lot-specific Certificate of Analysis documents both results for your records.
Bulk KPV is available in the catalog sizes above. A minimum inquiry quantity of 10 vials applies; contact us for larger requirements or custom synthesis quotes. All products are for laboratory research use only (RUO) — not for human or veterinary use.
See HPLC & COA quality standards · Shipping & payment information · Full bulk peptides catalog